Colobomatous Optic Neuropathy

    • Congenital cleft in optic disc tissue from faulty embryogenesis
    • Often misdiagnosed as glaucoma
    • Other congenital forebrain and non-brain anomalies are often present
    • Optic disc excavation extends inferotemporally
    • Cleft may also involve the retina, choroid, upper eyelid, iris
    • Can affect one eye or both
    • Associated non-progressive visual field defect
    • Glaucoma
    • Tilted optic disc of myopia
    • Large physiologic cup
    • Suspect optic disc coloboma if there are clefts in the eyelid or iris
    • Distinguish from high myopia, glaucoma
    • Order brain imaging to detect other forebrain anomalies
    • Be aware of the association with papillorenal syndrome
    • Optic disc and visual field defects will be lifelong and stable
    • Clinical outcome depends on other anomalies
    • Trap: optic disc coloboma is often misdiagnosed as glaucoma, initiating unnecessary treatment

    Optic Nerve And Chiasm Disorders

    Drusen Optic Neuropathy Colobomatous Optic Neuropathy Optic Pit Neuropathy Morning Glory Optic Neuropathy Hypoplastic Optic Neuropathy Typical Optic Neuritis Atypical Optic Neuritis Papillitis (Neuroretinitis) Non-arteritic Ischemic Optic Neuropathy Arteritic Ischemic Optic Neuropathy Posterior Ischemic Optic Neuropathy Hypotensive Ischemic Optic Neuropathy Radiation-induced Optic Neuropathy Diabetic Papillopathy Hypertensive Optic Disc Edema Papilledema Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) Compressive Optic Neuropathy: Overview Optic Neuropathy of Graves Disease Optic Nerve Sheath Meningioma Sphenoid Meningioma Craniopharyngioma Pituitary Adenoma Pilocytic Astrocytoma (Optic Glioma) Carotid Aneurysm Suprasellar Germinoma Infiltrative (Neoplastic) Optic Neuropathy Paraneoplastic Optic Neuropathy Traumatic Optic Neuropathy Toxic Optic Neuropathy Nutritional Deficiency Optic Neuropathy Dominantly-Inherited Optic Neuropathy Leber Hereditary Optic Neuropathy Primary Open Angle Glaucoma