Morning Glory Optic Neuropathy

    • Congenital funnel-shaped excavation of the posterior ocular wall that encompasses an anomalous optic disc
    • Severe vision deficit owing to absent optic nerve axons
    • Forebrain and carotid artery anomalies often present
    • Core features
      • Crater-like depression of the optic disc usually confined to one eye
      • Spoke-like retinal vessels emerging from the margins of the crater, giving rise to the term “morning glory”
      • Peripapillary speckled atrophic retinal and choroidal tissue
      • Poor vision and afferent pupil defect in the affected eye
    • Possible accompanying features
      • Serous retinal detachment
      • Dysplastic corpus callosum, basal encephalocele
      • Hypoplastic carotid arteries with prominent cranial base anastomoses (“moya moya disease”)
      • Hypopituitarism
    • Optic disc coloboma
    • Staphyloma
    • Myopic degeneration
    • Healed chorioretinitis
    • Explain that the affected eye will never see properly
    • Perform vascular and brain imaging in search of potentially life-threatening brain and vascular anomalies
    • Perform blood tests in search of impaired pituitary hormone function
    • Management is directed at the non-ophthalmic anomalies

    Optic Nerve And Chiasm Disorders

    Drusen Optic Neuropathy Colobomatous Optic Neuropathy Optic Pit Neuropathy Morning Glory Optic Neuropathy Hypoplastic Optic Neuropathy Typical Optic Neuritis Atypical Optic Neuritis Papillitis (Neuroretinitis) Non-arteritic Ischemic Optic Neuropathy Arteritic Ischemic Optic Neuropathy Posterior Ischemic Optic Neuropathy Hypotensive Ischemic Optic Neuropathy Radiation-induced Optic Neuropathy Diabetic Papillopathy Hypertensive Optic Disc Edema Papilledema Idiopathic Intracranial Hypertension (Pseudotumor Cerebri) Compressive Optic Neuropathy: Overview Optic Neuropathy of Graves Disease Optic Nerve Sheath Meningioma Sphenoid Meningioma Craniopharyngioma Pituitary Adenoma Pilocytic Astrocytoma (Optic Glioma) Carotid Aneurysm Suprasellar Germinoma Infiltrative (Neoplastic) Optic Neuropathy Paraneoplastic Optic Neuropathy Traumatic Optic Neuropathy Toxic Optic Neuropathy Nutritional Deficiency Optic Neuropathy Dominantly-Inherited Optic Neuropathy Leber Hereditary Optic Neuropathy Primary Open Angle Glaucoma